Clinical Trial

Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects

Recruiting Phase 2
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Summary
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience receiving the TMNB injection (secondary outcomes).
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2022-08-16; most recent amendment 2025-12-04.
Status change: Not Yet Recruiting → Recruiting 2022-10-24
Trial Details
NCT Number NCT05507164
Lead Sponsor Rutgers, The State University of New Jersey
Conditions Occlusion
Enrollment 20 participants
Start Date 2022-10-10
Primary Completion 2026-09 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2025-12-05