Clinical Trial

Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes

Study acronym: CREST
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
This observational study will enroll adults with open angle glaucoma (OAG) who had surgery to reduce intraocular pressure (IOP) using the CycloPen Micro-Interventional System. Consenting participants will be followed for 24 months after their surgery. Data regarding IOP, use of glaucoma medications, and any side effects related to the surgery will be collected from participants' preoperative examination, their surgery, and postoperative examinations.
Protocol Amendment History 10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2022-08-16; most recent amendment 2026-07-20.
Status change: Enrolling by Invitation → Active, Not Recruiting 2026-07-18
Status change: Not Yet Recruiting → Enrolling by Invitation 2022-08-19
Trial Details
NCT Number NCT05506423
Lead Sponsor Iantrek, Inc.
Conditions Open Angle Glaucoma
Enrollment 300 participants
Start Date 2022-08-17
Primary Completion 2026-12 (estimated)
Study Completion 2027-12 (estimated)
Updated on ClinicalTrials.gov 2026-07-22