Clinical Trial

Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases

Active, Not Recruiting Phase 2
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Record status
This record was last updated December 24, 2025 (before its estimated June 28, 2026 completion). Its status may not reflect the trial's current state.
Summary
This phase II trial studies the effect of neuropsychological evaluation and intervention in maintaining quality of life after radiation therapy in patients with cancer that has spread to the brain (metastases). Quality of life refers to the overall enjoyment of life. It holds varying meanings for different people and may evolve over time. For some individuals it implies autonomy, empowerment, capability, and choice; for others, security, social integration, or freedom from stress or illness. Neuropsychological evaluation is used to examine the cognitive (thinking) consequences of brain damage, brain disease, and severe mental illness. Deterioration of both quality of life and cognitive function is common when receiving radiation to the brain. Neuropsychological evaluation with a certified neuropsychologist may improve quality of life or cognitive function after radiation therapy.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2022-08-15; most recent amendment 2025-12-18.
Status change: Recruiting → Active, Not Recruiting 2025-02-06
Status change: Not Yet Recruiting → Recruiting 2022-11-18
Trial Details
NCT Number NCT05503251
Lead Sponsor Ohio State University Comprehensive Cancer Center
Conditions Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm
Enrollment 110 participants
Start Date 2022-08-30
Primary Completion 2026-06-28 (estimated)
Study Completion 2026-06-28 (estimated)
Updated on ClinicalTrials.gov 2025-12-24