Clinical Trial

MRI Hypoxia Study for Glioblastoma Multiforme (GBM) Radiation Therapy

Study acronym: MANGO
Recruiting
View on ClinicalTrials.gov →
Summary
This study is designed to evaluate the role of Oxygen Enhanced (OE) Magnetic resonance imaging (MRI) and Blood Oxygenation Level Dependent (BOLD) MRI in detecting regions of hypoxic tumour and to evaluate their use as imaging methods to selectively deliver targeted radiotherapy to regions of aggressive disease.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2022-08-09; most recent amendment 2026-05-15.
Status change: Not Yet Recruiting → Recruiting 2026-05-15
Trial Details
NCT Number NCT05500612
Lead Sponsor University of Sydney
Collaborators: The Brain Cancer Group
Conditions Glioblastoma Multiforme
Enrollment 20 participants
Start Date 2024-08-14
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-05-19