Factors Associated With an Evolution in the Quality of Life of Diabetic Patients With Chronic, Wound-free Charcot Foot

Charcot foot, characterized by progressive destructive damage to bone, soft tissue and tendons, involving joint dislocation in the ankle and foot, is a complication of diabetes that is still poorly understood by patients and caregivers. The clinical signs are non-specific and it is therefore largely underestimated due to a delay in diagnosis/lack of diagnosis.This study will be on a prospective multicenter cohort of patients with chronic Charcot's foot in France to evaluate the evolution of quality of life at 2 years, as well as predictive factors in order to better identify subjects with the worst outcome among this population. Our hypothesis is that, in patients with chronic Charcot foot, the deterioration in quality of life over time is primarily related to loss of foot and ankle functionality, foot and ankle deformity and the presence of foot wounds/comorbidities/severe diabetic complications.

NCT Number	NCT05491577
Lead Sponsor	Centre Hospitalier Universitaire de Nīmes
Conditions	Charcot Joint of Foot, Osteoarthropathy
Enrollment	150 participants
Start Date	2023-01-23
Primary Completion	2027-07-22 (estimated)
Study Completion	2028-01-22 (estimated)
Updated on ClinicalTrials.gov	2024-08-13