Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between echocardiography and catheterization, with an overestimation of the real gradient with echo (vs. cath) in most cases. Thus, the incidence of procedural-device failure may be lower than that reported in the ViV-TAVR literature,

NCT Number	NCT05459233
Lead Sponsor	Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Conditions	Aortic Valve Stenosis, Aortic Valve Regurgitation, Prosthesis Failure
Enrollment	310 participants
Start Date	2023-01-11
Primary Completion	2027-09-01 (estimated)
Study Completion	2029-09-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-24