Clinical Trial

Gastrointestinal Dysmotility on Aspiration Risk

Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
The hypothesis of this study is that esophageal and gastric dysmotility increase the risk of developing aspiration-associated symptoms in children with neurologic impairment. The investigators are conducting a ten week cross over study comparing prucalopride to famotidine for the treatment of aspiration-associated symptoms.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2022-07-08.
Status change: Not Yet Recruiting → Recruiting 2025-12-23
Trial Details
NCT Number NCT05455359
Lead Sponsor Boston Children's Hospital
Conditions Esophageal Motility Disorders, Gastric Motor Dysfunction, Aspiration Pneumonia, Gastro Esophageal Reflux
Enrollment 120 participants
Start Date 2025-02-13
Primary Completion 2027-05-31 (estimated)
Study Completion 2027-05-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-03