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Filter Lifespan in Continuous Renal Replacement Therapy

Study acronym: CRRTInfO
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated December 12, 2024 (before its estimated May 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Primary completion date: Oct 2024 to May 2025
    • Study sites: 3 to 5
    • Study completion date: Jan 2025 to Aug 2025
    v6
  2. Study sites: 1 to 3v5
  3. Re-verified, no change to tracked fieldsv4
  4. Trial status: Not Yet Recruiting to Recruitingv3 Show 4 more changesShow less
    • Primary completion date: Mar 2024 to Oct 2024
    • Start date changed from estimate of Nov 2022 to Mar 2, 2023
    • Study completion date: Aug 2024 to Jan 2025
    • Site details revised
  5. Start date: Sep 2022 to Nov 2022v2
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The only supportive therapy for patients with AKI is renal replacement therapy (RRT). In the ICU setting, continuous RRT (CRRT) is mostly favored. In a post-hoc analysis of the RICH trial (regional citrate versus systemic heparin anticoagulation for CRRT in critically ill patient with AKI), it was shown that the filter life span is associated with an increased rate of new infection and that the type of anticoagulants did not directly affect infection rate. The mechanisms of this infection rate is unknown.
Trial Details
NCT Number NCT05450185
Lead Sponsor University Hospital Muenster
Collaborators: Baxter Healthcare Corporation
Conditions
(from sponsor)		 Critically Ill, Continuous Renal Replacement Therapy, Infections
Related terms Critical Illness, Infections
Enrollment 600 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov