Engaging Staff to Improve COVID-19 Vaccination Response at Long-Term Care Facilities

The ENSPIRE study is a cluster-randomized comparative effectiveness trial being conducted within long-term care and residential facilities that will test a communication and engagement strategy for increasing COVID-19 booster vaccination rates against an enhanced usual care comparator (Centers for Disease Control and Prevention or other national organization vaccine education and communication materials) among facility staff. The communication and engagement strategy being tested includes (1) the development of materials co-designed with and tailored to facility staff whose primary language is a language other than English or who are from certain cultural affinity groups and (2) the distribution of the developed materials by members of the language/cultural affinity groups with peer advocacy activities (full intervention). The study is being conducted in Washington state and Georgia. Long-term care/residential facilities will be asked to furnish their staff booster rate at 4 timepoints: pre-intervention, and one month (timepoint 1), 3 months (timepoint 2), and 6 months (timepoint 3) post-intervention. Staff at participating long-term care facilities will be invited to complete three online surveys at 3 timepoints: pre-intervention, 3 months post-intervention and 6 months post-intervention. Long-term care facilities will be randomized to a trial arm following the pre-intervention data collection.

NCT Number	NCT05449418
Lead Sponsor	Kaiser Permanente Collaborators: Patient-Centered Outcomes Research Institute, Global Alliance to Prevent Prematurity and Stillbirth (GAPPS)
Conditions	COVID-19
Enrollment	988 participants
Start Date	2021-08-01
Primary Completion	2024-07-31 (estimated)
Study Completion	2026-02-28 (estimated)
Updated on ClinicalTrials.gov	2024-09-19