Clinical Trial

A Study on Predictive Models and Clinical Outcome of Radiation Pneumonitis

Recruiting
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Summary
Radiation pneumonitis is the main dose-limiting toxicity of thoracic radiotherapy, which can affect life quality, survival, and the tumor-controlling effects of patients receiving thoracic radiotherapy. The purpose of this study is to: * Identify biomarkers including serum proteins, gene expression, genetic changes, and epigenetic modifications that determine radiation pneumonitis. * Investigate the relationship between radiation pneumonitis and other toxicities induced by radiotherapy. * Construct a predictive model for radiation pneumonitis. * Evaluate survival and treatment outcome of patients with radiation pneumonitis.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2022-07-02.
Trial Details
NCT Number NCT05448703
Lead Sponsor Huazhong University of Science and Technology
Collaborators: Hubei Cancer Hospital, Jingjiang People' Hospital
Conditions Radiation Pneumonitis
Enrollment 300 participants
Start Date 2021-02-25
Primary Completion 2026-09-01 (estimated)
Study Completion 2026-09-01 (estimated)
Updated on ClinicalTrials.gov 2022-10-06