GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries

The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery. Spinal anesthesia in decompressive procedures can be the new standard of care. Recently, it has been found that regional analgesia is option that has been shown to improve pain and opioid-related outcomes after spine surgery, but has not yet been studied in combination with spinal anesthesia. This is study that consists of two groups: standard of care general anesthesia with a nerve block and a spinal anesthesia with nerve block. Patients are randomized to either of the two groups. There will be 71 patients enrolled in each group for this study.

NCT Number	NCT05444751
Lead Sponsor	Hospital for Special Surgery, New York
Conditions	Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
Enrollment	142 participants
Start Date	2022-03-22
Primary Completion	2026-09 (estimated)
Study Completion	2026-09 (estimated)
Updated on ClinicalTrials.gov	2026-04-28