Clinical Trial

Liver Fat as a Dietary Target of the Chinese Medical Nutrition Therapy (CMNT) Diet for Treating Type 2 Diabetes With Nonalcoholic Fatty Liver Disease

Recruiting
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Record status
This record was last updated July 25, 2025 (before its estimated May 5, 2026 completion). Its status may not reflect the trial's current state.
Summary
Type 2 diabetes (T2D) represents a serious public health problem. Patients with T2D and non-alcoholic fatty liver disease(NAFLD) demonstrate a poor metabolic profile and increase mortality compared with patients with only NAFLD or T2D. Nutritional intervention is the most basic treatment for T2D. Previous study showed that a Chinese medical nutrition therapy (CMNT) diet, which intermittent use of low-calorie medicinal food, has a glucose-lowering effect in T2D. This study aims to investigate the effect of a Chinese medical nutrition therapy (CMNT) diet accompanied by intermittent energy restriction on reducing liver fat and glycated hemoglobin (HbA1c) in patients with T2D and NAFLD.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2022-06-27; most recent amendment 2025-07-22.
Trial Details
NCT Number NCT05439226
Lead Sponsor State Key Laboratory of Subhealth Intervention Technology
Conditions Type 2 Diabetes
Enrollment 120 participants
Start Date 2022-07-05
Primary Completion 2026-05-05 (estimated)
Study Completion 2026-06-05 (estimated)
Updated on ClinicalTrials.gov 2025-07-25