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NCT05437341 · ClinicalTrials.gov record · last posted 2026-08-24

PSMA/CD70 Bi-specific CAR-T Cell Therapy

Name: PSMA/CD70 Bi-specific CAR-T Cell Therapy — clinical trial record (NCT05437341)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusTerminated

PhasePhase 1/2

SponsorShenzhen Geno-Immune Medical Institute

Started2026-06-01

View on ClinicalTrials.gov ↗

from the ClinicalTrials.gov record

The purpose of this study is to assess the feasibility, safety and efficacy of anti-PSMA/CD70 bi-specific CAR-T cell therapy in patients with CD70 and PSMA positive malignancies. Another goal of the study is to learn more about the function of the PSMA/CD70 bi-specific CAR-T cells and their persistency in patients.

Protocol amendment history 3 changes detected by DataLookout

2026-08-25

Trial terminated

2026-08-25

Primary completion moved earlier: 2026-12-31 → 2026-07-01

2026-08-25

Completion moved earlier: 2030-12-31 → 2026-07-31

Trial Details

NCT Number	NCT05437341
Lead Sponsor	Shenzhen Geno-Immune Medical Institute
Conditions	Cancer Disease
Enrollment	60 participants
Start Date	2026-06-01
Primary Completion	2026-07-01 (estimated)
Study Completion	2026-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-24