Clinical Trial

PRP in ACLR to Prevent PTOA

Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2022-06-07; most recent amendment 2026-02-11.
Trial Details
NCT Number NCT05412381
Lead Sponsor Hospital for Special Surgery, New York
Collaborators: Orthopedic Research and Education Foundation
Conditions Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP
Enrollment 56 participants
Start Date 2022-06-27
Primary Completion 2026-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-13