PICO 7 vs PICO 14 in Revision Hip and Revision Knee Surgery.

This is a single-site trial, and it has been designed to compare a revision hip cohort with a revision knee cohort. All consecutive eligible patients, under the care of participating Co-Investigator Orthopaedic Surgeons, are approached for recruitment into the study. Eligible patients wishing to participate must require either revision hip or revision knee surgery and consent to be randomised to either NPWT PICO dressing for 7-day therapy (PICO 7) or NPWT PICO 14-day therapy (PICO 14). 82 Revision Hips and 82 Revision Knee participants, with 41\* of each cohort randomised to either a 7-day or a 14-day NPWT dressing treatment duration period. The 7-day cohort will be treated with PICO7 dressings and pumps, and the 14-day cohort will be treated with PICO14 dressings. \*Randomisation will be stratified, so it will continue until there are at least 41 participants in each cohort.

NCT Number	NCT05389410
Lead Sponsor	Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Conditions	Surgical Wound
Enrollment	164 participants
Start Date	2024-02-14
Primary Completion	2026-02-14 (estimated)
Study Completion	2027-02-14 (estimated)
Updated on ClinicalTrials.gov	2024-03-25