Clinical Trial

Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area and left inferior frontal gyrus) thought to aid in memory will improve speech and language difficulties in patients with primary progressive aphasia (PPA) and progressive apraxia of speech (PAOS). The primary outcome measures are neuropsychological assessments of speech and language functions, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures.
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2022-05-05; most recent amendment 2026-05-06.
Status change: Enrolling by Invitation → Active, Not Recruiting 2025-04-30
Status change: Recruiting → Enrolling by Invitation 2024-04-04
Trial Details
NCT Number NCT05368350
Lead Sponsor The University of Texas at Dallas
Conditions Primary Progressive Aphasia, Apraxia of Speech
Enrollment 12 participants
Start Date 2022-06-01
Primary Completion 2027-04-16 (estimated)
Study Completion 2027-04-16 (estimated)
Updated on ClinicalTrials.gov 2026-05-08