Clinical Trial

Physiological Ventricular Pacing Vs Managed Ventricular Pacing for Persistent AF Prevention in Prolonged AV Interval

Study acronym: PhysioVP-AF
Recruiting
View on ClinicalTrials.gov →
Summary
A multicenter, prospective, randomized study in a 1:1 ratio, single-blind with double-blind evaluation to evaluate the superiority of physiological ventricular pacing (proposed modality) vs. managed ventricular pacing (control) for prevention of persistent AF (PeAF) occurrence in patients with prolonged atrioventricular interval (PR≥180 ms) and indication for pacing: sinus node disease and/or paroxysmal type 1 or 2-second degree AV block.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2022-05-04; most recent amendment 2025-05-06.
Status change: Not Yet Recruiting → Recruiting 2022-08-16
Trial Details
NCT Number NCT05367037
Lead Sponsor Quovadis Associazione
Conditions Sinus Node Disease, Atrioventricular; Block, Second Degree (Types I and II)
Enrollment 640 participants
Start Date 2022-07-27
Primary Completion 2028-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2025-05-11