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Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated September 18, 2025 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary and study completion dates: Jun 30, 2025 to Jun 30, 2026
    • Site contact updated
    v4
  2. Primary and study completion dates: Jun 30, 2024 to Jun 30, 2025
    • Site contact updated
    v3
  3. Lead sponsor: Harvard Medical School (HMS and HSDM) to Boston VA Research Institute, Inc.
    • Collaborators: 2 to 3
    v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.
Trial Details
NCT Number NCT05299749
Lead Sponsor Boston VA Research Institute, Inc.
Collaborators: Mclean Hospital, Northeastern University, Cambridge Health Alliance
Conditions
(from sponsor)		 Schizophrenia, Auditory Hallucination, Treatment-resistant Schizophrenia
Related terms Hallucinations, Schizophrenia, Schizophrenia, Treatment-Resistant
Enrollment 104 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov