Clinical Trial

the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis

Active, Not Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated February 12, 2026 (before its estimated April 26, 2026 completion). Its status may not reflect the trial's current state.
Summary
In this study it is investigated whether treatment with azithromycin in combination with doxycycline reduces the bacterial load of C. acnes in granulomatous tissue of patients with sarcoidosis and subsequently decreases the inflammatory activation measured by FDG uptake and serum biomarkers.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2022-03-12; most recent amendment 2026-02-10.
Status change: Not Yet Recruiting → Active, Not Recruiting 2026-02-10
Trial Details
NCT Number NCT05291468
Lead Sponsor St. Antonius Hospital
Collaborators: ZonMw: The Netherlands Organisation for Health Research and Development
Conditions Sarcoidosis, Pulmonary, Sarcoidosis Skin
Enrollment 40 participants
Start Date 2023-02-15
Primary Completion 2026-04-26 (estimated)
Study Completion 2026-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-12