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the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis

StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 12, 2026 (before its estimated April 26, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Primary completion date: Apr 30, 2023 to Apr 26, 2026v4 Show 4 more changesShow less
    • Trial status: Not Yet Recruiting to Active, Not Recruiting
    • Study completion date: Jun 30, 2023 to Dec 1, 2026
    • Start date changed from estimate of Jan 1, 2023 to Feb 15, 2023
    • Site contact updated
  2. Start date: Apr 1, 2022 to Jan 1, 2023v3
  3. Secondary endpoints: details revised at 1 of 2 entriesv2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
In this study it is investigated whether treatment with azithromycin in combination with doxycycline reduces the bacterial load of C. acnes in granulomatous tissue of patients with sarcoidosis and subsequently decreases the inflammatory activation measured by FDG uptake and serum biomarkers.
Trial Details
NCT Number NCT05291468
Lead Sponsor St. Antonius Hospital
Collaborators: ZonMw: The Netherlands Organisation for Health Research and Development
Conditions
(from sponsor)		 Sarcoidosis, Pulmonary, Sarcoidosis Skin
Related terms Sarcoidosis, Pulmonary
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov