Collaborative Approach to Reach Everyone With Familial Hypercholesterolemia (CARE-FH)

Diagnosis rates of familial hypercholesterolemia (FH) are low in the United States, despite multiple guidelines and recommendations for screening and treatment of high cholesterol, to prevent heart attacks in those affected. Using a stepped-wedge design, the investigators plan to utilize tools from implementation science to improve uptake, acceptability, and sustainability of FH diagnostic programs in primary care settings. If successful, this study will provide tools generalizable to other health care systems to improve FH diagnosis rates.

NCT Number	NCT05284513
Lead Sponsor	Geisinger Clinic Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions	Familial Hypercholesterolemia
Enrollment	532 participants
Start Date	2022-09-09
Primary Completion	2027-01 (estimated)
Study Completion	2027-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-22