Clinical Trial

Functional Evaluation After Breast Reconstruction With a Minimally Invasive Latissimus Dorsi Flap Following Radical Surgery for Breast Cancer.

Study acronym: BREAST
Active, Not Recruiting
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Record status
This record was last updated December 26, 2025 (before its estimated March 6, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study will quantify the muscle function after breast reconstruction using a minimally invasive latissimus dorsi flap. The proposed measures (clinical, isokinetic, electrophysiology, function and quality of life questionnaires) allow a precise, multidisciplinary, objective evaluation of the capacity of the latissimus dorsi muscle before surgery, 3 months, 6 months and 12 months after surgery. A function deficit is expected (decreased moment of adduction and internal rotation) 3 months after surgery and a return to the preoperative state 6 months and 12 months after surgery.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2022-03-03; most recent amendment 2025-12-19.
Status change: Recruiting → Active, Not Recruiting 2025-12-19
Status change: Not Yet Recruiting → Recruiting 2023-10-16
Trial Details
NCT Number NCT05278741
Lead Sponsor Centre Georges Francois Leclerc
Conditions Breast Cancer
Enrollment 32 participants
Start Date 2022-11-25
Primary Completion 2026-03-06 (estimated)
Study Completion 2026-12-04 (estimated)
Updated on ClinicalTrials.gov 2025-12-26