Clinical Trial

Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity

Unknown
View on ClinicalTrials.gov →
Record status
This record was last updated July 5, 2024 (before its estimated January 31, 2025 completion). Its status may not reflect the trial's current state.
Summary
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha). These data will be correlated with serum values and disease status. In addition, organoids from duodenal tissue will be isolated and cultured in vitro and stimulated with the major food allergens. The gene and protein expression will be checked to identify relevant biomarkers.
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Unknown 2026-08-02
Trial Details
NCT Number NCT05259826
Lead Sponsor University of Erlangen-Nürnberg Medical School
Conditions Food Allergy, Food Hypersensitivity
Enrollment 115 participants
Start Date 2022-02-01
Primary Completion 2025-01-31 (estimated)
Study Completion 2025-01-31 (estimated)
Updated on ClinicalTrials.gov 2024-07-05