Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial

This is a prospective randomized controlled trial comparing two ways of delivering Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR) therapy for posttraumatic stress disorder (PTSD). The study seeks 60 volunteers who have PTSD and are eligible for care in the Department of Defense healthcare system. There will be 10-14 therapy sessions that are 60-90 minutes long, about once a week, and symptoms will be assessed before and after the therapy as well as 3 and 6 months after completing therapy. 3MDR asks you to choose pictures and music that are integrated into a virtual reality environment. You will be walking on a treadmill throughout each therapy session, while the therapist stands next to the treadmill and asks you questions about the pictures you chose.

NCT Number	NCT05244564
Lead Sponsor	Uniformed Services University of the Health Sciences Collaborators: Military Traumatic Brain Injury Initiative, USUHS, Center for Rehabilitation Sciences Research, USUHS
Conditions	Stress Disorders, Post-Traumatic
Enrollment	60 participants
Start Date	2023-04-30
Primary Completion	2027-05-31 (estimated)
Study Completion	2027-10-30 (estimated)
Updated on ClinicalTrials.gov	2025-07-15