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Pharmacotyping of Pancreatic Patient-derived Organoids

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated October 3, 2024 (before its estimated August 30, 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Notable Trial status: Active, Not Recruiting to Recruiting
    • Primary completion date: Apr 30, 2024 to Aug 30, 2025
    • Study completion date: Dec 31, 2024 to Aug 31, 2025
    • Site details revised
    v6
  2. Notable Primary completion date: Oct 30, 2023 to Apr 30, 2024v5
  3. Minor Trial status: Recruiting to Active, Not Recruiting
    • Enrollment target: estimated 40 to confirmed 88
    • Primary completion date: Jun 30, 2023 to Oct 30, 2023
    • Site details revised
    v4
  4. Minor 2 versions Re-verified since Jan 19, 2022, no change to tracked fieldsv2-v3
  5. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
EUS-FNB samples will be used for organoid cultures, which will be co-cultured with cancer associated fibroblasts derived from the surrounding stroma of the lesion. The organoid cultures will be used for pharmacotyping using relevant chemotherapeutic agents used in the clinic, and the organoid's response compared with the patient's response.
Trial Details
NCT Number NCT05196334
Lead Sponsor Herlev Hospital
Collaborators: Rigshospitalet, Denmark
Conditions
(from sponsor)
Pancreatic Cancer
Related terms Pancreatic Neoplasms
Enrollment 88 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov