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Genetic and Cognitive Predictors of Aphasia Treatment Response

StatusCompleted
PhaseNot applicable
Started
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Record History

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  1. Trial completed Show 5 more changesShow less
    • Primary completion pushed from Jul 1, 2026 to Sep 21, 2026
    • Final enrollment: 35 participants (planned 120)
    • Study completion date changed from estimate of Aug 31, 2026 to Sep 21, 2026
    • Eligibility criteria expanded, about 10 words
    • Collaborators: details revised at 1 of 1 entry
  2. Primary completion pushed from Apr 2026 to Jul 1, 2026
    • Study completion pushed from May 2026 to Aug 31, 2026
    v5
  3. Primary completion date: Aug 2025 to Apr 2026
    • Trial status: Recruiting to Active, Not Recruiting
    • Study completion date: Aug 2025 to May 2026
    • Site details revised
    v4
  4. Site contact updatedv3
  5. Primary completion date: May 2024 to Aug 2025
    • Study completion date: Aug 2024 to Aug 2025
    v2
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Aphasia, or language impairment after a stroke, affects approximately 2 million people in the United States, with an estimated 180,000 new cases each year. The medical community cannot predict how well someone with aphasia will respond to treatment, as some people with aphasia are poor responders to intervention even when participating in empirically supported treatments. There is a strong likelihood that genetics play a role in language recovery after stroke, but very little research has been dedicated to investigating this link. This study will investigate whether two genes and cognitive abilities, such as memory, predict responsiveness to aphasia therapy for word-retrieval difficulties.
Trial Details
NCT Number NCT05179538
Lead Sponsor Ohio State University
Collaborators: Nationwide Children's Hospital
Conditions
(from sponsor)		 Aphasia
Related terms Aphasia
Enrollment 35 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov