Clinical Trial

Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome

Study acronym: IRM SAOS
Recruiting
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Summary
The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wakefulness. The objective of this study is to test whether awake OSAS patients would exhibit a similar cortical activity. Whether or not such cortical compensatory mechanisms have cognitive consequences would be also analyze.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2021-11-29; most recent amendment 2025-11-28.
Trial Details
NCT Number NCT05147649
Lead Sponsor CHU de Reims
Conditions Obstructive Sleep Apnea Syndrome
Enrollment 70 participants
Start Date 2023-03-02
Primary Completion 2027-01-02 (estimated)
Study Completion 2027-07-02 (estimated)
Updated on ClinicalTrials.gov 2025-12-02