Clinical Trial

Neurostimulation to Improve NOWS Outcomes

Study acronym: SPROUT
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The objective of this study is to determine if tAN therapy can reduce the median number of days of oral morphine administered to an infant after start of treatment.
Protocol Amendment History 31 amendments
This ClinicalTrials.gov record has been amended 31 times since 2021-11-19; most recent amendment 2026-06-09.
Status change: Recruiting → Active, Not Recruiting 2025-02-03
Status change: Not Yet Recruiting → Recruiting 2022-08-01
Trial Details
NCT Number NCT05129020
Lead Sponsor Spark Biomedical, Inc.
Collaborators: Medical University of South Carolina, University of Texas Southwestern Medical Center, The University of Texas Health Science Center at San Antonio, National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH)
Conditions Neonatal Opioid Withdrawal Syndrome, Neonatal Abstinence Syndrome
Enrollment 52 participants
Start Date 2022-07-27
Primary Completion 2025-01-31 (estimated)
Study Completion 2027-01-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-02