PENG vs. FIC Block for Hip Fracture ED Patients

StatusCompleted
PhaseNot applicable
Started

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Record History

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  1. Minor Trial completed Show 4 more changesShow less
    • Final enrollment: 50 participants (planned 80)
    • Primary completion date changed from estimate of Jun 30, 2026 to May 31, 2026
    • Study completion date changed from estimate of Dec 31, 2026 to Jun 21, 2026
    • Eligibility criteria expanded, about 11 words
  2. Notable Primary completion date: Jun 30, 2025 to Jun 30, 2026
    • Trial status: Recruiting to Active, Not Recruiting
    • Study completion date: Dec 31, 2025 to Dec 31, 2026
    • Site details revised
    v7
  3. Minor Re-verified, no change to tracked fieldsv6
  4. Notable Primary completion date: Jun 30, 2024 to Jun 30, 2025
    • Study completion date: Dec 31, 2024 to Dec 31, 2025
    v5
  5. Notable Primary completion date: Dec 31, 2023 to Jun 30, 2024
    • Study completion date: Dec 31, 2023 to Dec 31, 2024
    v4
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  1. Minor Re-verified, no change to tracked fieldsv3
  2. Notable Primary and study completion dates: Dec 31, 2022 to Dec 31, 2023v2
  1. Minor Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Ultrasound-guided nerve blocks are an important tool for treating pain due to orthopedic injury in the ED. They provide long lasting, opioid-sparing pain relief that is generally safe and well-tolerated by patients1. Elderly patients with hip fractures commonly present to the ED, and their injury can be painful. Commonly used opioid pain regimens can have deleterious side effects, especially in elderly patients, like somnolence, delirium, hypotension and respiratory depression. The fascia iliaca compartment (FIC) block has become a familiar technique to emergency physicians as a pain control treatment for hip fractures. The pericapsular nerve group (PENG) block has recently been proposed as a novel method to treat pain due to hip, acetabular and pelvic fracture by targeting the terminal sensory articular nerve branches of the femoral nerve (FN), obturator nerve (ON), and accessory obturator nerve (AON). At this time there has been no study comparing the efficacy of the two nerve blocks, PENG and FIC. This aim of this study is to compare the efficacy of the PENG block (20mL of Bupivacaine 0.50%) to that of the FIC block (40mL of Bupivacaine 0.25%) for patients with hip fractures in the ED. Our hypothesis is that PENG will demonstrate analgesia that is non-inferior to FIC. Subjective pain scores on a scale of 0 to 10 will be assessed before and after the block. All subjects will receive 4mg of morphine after consent and prior to the block.
Trial Details
NCT Number NCT05102760
Lead Sponsor Antonios Likourezos
Conditions
(from sponsor)
Pain, Hip Fracture
Related terms Hip Fractures, Pain
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov