Clinical Trial

The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury

Study acronym: KETA-BID
Recruiting Phase 4
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Summary
Cortical spreading depolarisations are pathological depolarisation waves that occur frequently after severe acute brain injury and has been associated with poor outcome. S-ketamine has been shown to inhibit cortical spreading depolarisations. The aim of the present study is to examine the efficacy and safety of using S-ketamine for treatment of patients with severe acute brain injury, as well as the feasibility of the trial design.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2021-10-14; most recent amendment 2024-06-24.
Status change: Not Yet Recruiting → Recruiting 2023-09-20
Trial Details
NCT Number NCT05095857
Lead Sponsor Rigshospitalet, Denmark
Collaborators: Copenhagen Trial Unit, Center for Clinical Intervention Research
Conditions Subarachnoid Hemorrhage, Aneurysmal, Intracerebral Hemorrhage, Traumatic Brain Injury
Enrollment 400 participants
Start Date 2023-09-15
Primary Completion 2028-09-15 (estimated)
Study Completion 2028-09-15 (estimated)
Updated on ClinicalTrials.gov 2024-06-26