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Neural Mechanisms for Reducing Interference During Episodic Memory Formation

StatusEnrolling by Invitation
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 11 months later Dec 2025 → Dec 2026
See other at-risk trials from University of Oregon

Record History

  1. Primary completion pushed from Dec 2025 to Dec 2026
    • Enrollment increased: 737 → 2900 participants
    • Study completion pushed from Jan 2026 to Jan 2027
    v5
  2. Primary completion date: Jun 2025 to Dec 2025
    • Study completion date: Jun 2025 to Jan 2026
    • Interventions: Eye tracking (Other), Visual stimulus similarity (Behavioral), fMRI (Other) to Eye tracking (Behavioral), Visual stimulus similarity (Behavioral), fMRI (Other)
    v4
  3. Re-verified, no change to tracked fieldsv3
  4. Trial status: Not Yet Recruiting to Enrolling by Invitation
    • Start date changed from estimate of Nov 2021 to Sep 29, 2021
    • Site contact updated
    v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Healthy individuals from the University of Oregon and surrounding community will be recruited for participation in behavioral, fMRI and eye tracking experiments that investigate human memory. Recruitment will involve emails, flyers, and local advertisements. Individuals between the ages of 18-80 (or 18-35 for some studies) will be eligible. The broad objective of the research is to understand how humans form distinct memories for similar experiences. Experimental sessions will involve studying and trying to remember various images (e.g., images of natural scenes). The intervention will involve manipulating the similarity and/or learning protocol for the studied images. Outcome measures will include (a) behavioral measures of memory, and/or (b) fMRI measures of hemodynamic activity, and/or (c) eye tracking measures of gaze direction. Experimental sessions will last approximately 1-3 hours.
Trial Details
NCT Number NCT05092100
Lead Sponsor University of Oregon
Conditions
(from sponsor)		 Behavior
Related terms Behavior
Enrollment 2,900 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov