Clinical Trial

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Recruiting Early Phase 1
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Summary
This study is to investigate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy in patients with advanced solid tumors. Autologous TILs are expanded from tumor resections or biopsies and infused i.v. into the patient after NMA lymphodepletion treatment with hydroxychloroquine(600mg,single-dose) and cyclophosphamide.
Trial Details
NCT Number NCT05087745
Lead Sponsor Shanghai Juncell Therapeutics
Collaborators: Sir Run Run Shaw Hospital
Conditions Advanced Solid Tumor, Tumor Infiltrating Lymphocytes, Treatment Side Effects, Effects of Immunotherapy
Enrollment 50 participants
Start Date 2021-12-10
Primary Completion 2027-12-10 (estimated)
Study Completion 2029-12-10 (estimated)
Updated on ClinicalTrials.gov 2026-08-05