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Investigating the Tumour Immune Response of Radiotherapy

Study acronym: TIMM-RAD
StatusRecruiting
PhaseNot specified
Started
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Record status
This record was last updated June 11, 2025 (before its estimated July 14, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary completion date: Jul 14, 2024 to Jul 14, 2026
    • Study completion date: Jun 14, 2025 to Aug 14, 2026
    v3
  2. Primary completion date: Jun 1, 2023 to Jul 14, 2024v2 Show 5 more changesShow less
    • Enrollment target: 100 to 120
    • Study completion date: Jun 1, 2024 to Jun 14, 2025
    • Eligibility criteria expanded, about 24 words
    • Study description expanded, about 7 words
    • Study arms: 5 to 6
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study aims to investigate immune changes which occur before and following standard radiotherapy in a range of tumour types. We will collect tissue and blood samples before and after radiation treatment from participants across six cancer types: cervical, rectal, Head and Neck cancer, nodal non-Hodgkin lymphoma, cutaneous lymphoma and cutaneous squamous cell carcinoma/ basal cell carcinoma.
Trial Details
NCT Number NCT05076500
Lead Sponsor University of Manchester
Collaborators: The Christie NHS Foundation Trust
Conditions
(from sponsor)		 Cancer
Related terms Neoplasms
Enrollment 120 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov