Clinical Trial

Effect of Inulin on Gut Microbiota and Gut Barrier in Chronic Kidney Disease

Study acronym: RESTORE
Recruiting
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Record status
This record was last updated June 25, 2024 (before its estimated February 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
An adequate fiber intake is crucial for a well-balanced diet and reduces the risk of chronic diseases. However, nutritional recommendations for chronic kidney disease patients lead to an insufficient fiber intake with possible maladaptive effects on the gut microbiome. Therefore, we want to study the effects of a 35-day inulin supplementation on the gut microbiome, gut barrier function, bacterial metabolites and immune cell states in chronic kidney disease patients.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2021-09-27; most recent amendment 2024-06-24.
Status change: Not Yet Recruiting → Recruiting 2022-02-18
Trial Details
NCT Number NCT05071131
Lead Sponsor Charite University, Berlin, Germany
Conditions Chronic Kidney Disease 5D
Enrollment 40 participants
Start Date 2022-02-01
Primary Completion 2026-02-01 (estimated)
Study Completion 2027-02-01 (estimated)
Updated on ClinicalTrials.gov 2024-06-25