Case Control Study to Identify Modifiable Risk Factors for Colorectal and Breast Cancer in Nigeria

This project is a case-control study which seeks to identify modifiable risk factors for breast and colorectal cancer in Nigeria. Both cases and controls will be required to complete a risk factor questionnaire which contains information about their diet, physical activity, past medical history and life style factors. They will also be required to provide information on their body composition through the use of a bioimpedance machine which measures the body mass index, fat and total body water percentage. Based on the existing ARGO platform where a current colorectal cancer study is going on, approximately 400 patients with a prior diagnosis or a new diagnosis will be recruited into this study. Comparatively, we will select our 400 controls from two groups of participants who are free of cancer and gastrointestinal diseases.

NCT Number	NCT05044689
Lead Sponsor	Obafemi Awolowo University Teaching Hospital Collaborators: Memorial Sloan Kettering Cancer Center, Lagos State University, University of Ilorin Teaching Hospital, Federal Medical Centre, Owo, University of Maiduguri Teaching Hospital, National Hospital, Abuja
Conditions	Colorectal Cancer, Breast Cancer
Enrollment	800 participants
Start Date	2021-04-12
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-03-21