Clinical Trial

Inguinal Node Sparing Radiotherapy For Patients With Early Stage Anal Cancer

Study acronym: INSPIRE
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The purpose of this study is to see whether avoiding preventative radiation to the groin in patients with normal sentinel node biopsy and PET-CT, is at least as effective treating cancer as giving preventative radiation to the groin for patients with anal canal cancer. The investigators also want to know if avoiding radiation to the groin will cause fewer side effects and better quality of life
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2021-09-01; most recent amendment 2025-10-01.
Status change: Not Yet Recruiting → Recruiting 2023-05-12
Trial Details
NCT Number NCT05040815
Lead Sponsor AHS Cancer Control Alberta
Conditions Anal Canal Cancer
Enrollment 45 participants
Start Date 2023-05-11
Primary Completion 2028-05 (estimated)
Study Completion 2028-05 (estimated)
Updated on ClinicalTrials.gov 2025-10-02