Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment

The proposed IMPOWR Research Center at Montefiore-Einstein (IMPOWR-ME) will create a multidisciplinary and synergistic program of research to test multimodal treatments that address both chronic pain and opioid use disorder. IMPOWR-ME will generate critical knowledge about the effectiveness, implementation, and cost effectiveness of providing Acceptance and Commitment Therapy and/or a care management smartphone app for individuals in primary care-based buprenorphine treatment. Patients with lived experience with chronic pain and/or opioid use disorder, patient and policy advocates, payors, and health system partners will be engaged in all stages of the research. IMPOWR-ME is well-positioned to become a long-lasting hub for stakeholder-engaged research with multidisciplinary senior and early stage investigators focused on reducing overdose through better treatments for OUD and CP.

NCT Number	NCT05039554
Lead Sponsor	Albert Einstein College of Medicine Collaborators: National Institute on Drug Abuse (NIDA), Weill Medical College of Cornell University, Wake Forest University Health Sciences, University of Miami, Valera Health, Tulane University
Conditions	Opioid-use Disorder, Chronic Pain
Enrollment	125 participants
Start Date	2023-02-02
Primary Completion	2027-04-29 (estimated)
Study Completion	2027-04-29 (estimated)
Updated on ClinicalTrials.gov	2026-07-15