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NCT05039424 · ClinicalTrials.gov record · last posted 2026-07-13

Endoscopic Myotomy of the Pylorus To Improve Emptying and Symptoms Trial

Name: Endoscopic Myotomy of the Pylorus To Improve Emptying and Symptoms Trial — clinical trial record (NCT05039424)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: EMPTIES

StatusActive, Not Recruiting

PhaseNot applicable

SponsorMatthew Allemang

Started2022-02-23

View on ClinicalTrials.gov ↗

from the ClinicalTrials.gov record

A randomized clinical trial comparing endoscopic per-oral pyloromyotomy (POP) versus a control sham intervention (diagnostic esophagogastroduodenoscopy (EGD) without pyloric disruption) in patients with medically refractory gastroparesis.

Protocol amendment history 2 changes detected by DataLookout

2026-07-14

Primary completion moved earlier: 2026-07 → 2026-03-31

2026-07-14

Completion pushed: 2026-07 → 2027-03-01

Trial Details

NCT Number	NCT05039424
Lead Sponsor	Matthew Allemang Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions	Gastroparesis
Enrollment	100 participants
Start Date	2022-02-23
Primary Completion	2026-03-31 (estimated)
Study Completion	2027-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-13