Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis

The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) can lessen pain, improve function, and improve patient satisfaction in cases of knee osteoarthritis. CBD comes from the cannabis plant and is non-psychoactive (i.e. does not produce a 'high' or altered mental state) as compared to tetrahydrocannabinol (THC), another compound found in cannabis. Researchers are studying different forms of CBD for potential use in treating pain, inflammation, and illnesses.

NCT Number	NCT05020028
Lead Sponsor	NYU Langone Health Collaborators: Orcosa Inc.
Conditions	Knee Arthritis
Enrollment	100 participants
Start Date	2022-06-22
Primary Completion	2027-09 (estimated)
Study Completion	2027-09 (estimated)
Updated on ClinicalTrials.gov	2026-06-09