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Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes

Study acronym: MOMSPlacenta
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 12, 2026 (before its estimated September 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion date: Sep 30, 2025 to Sep 30, 2026
    • Trial status: Recruiting to Active, Not Recruiting
    • Study completion date: Dec 31, 2025 to Dec 31, 2026
    • Site details revised
    v8
  2. Lead sponsor: University of the Incarnate Word to Henry M. Jackson Foundation for the Advancement of Military Medicine
    • Collaborators: 3 to 4
    v7
  3. Study description shortened, about 10 words
    • Site contact updated
    v6
  4. Enrollment target: 1200 to 150v5
  5. Trial status: Active, Not Recruiting to Recruitingv4 Show 5 more changesShow less
    • Primary endpoints revised (3)
    • Eligibility criteria revised
    • Study description expanded, about 131 words
    • Site details revised
    • Collaborators: 2 to 3
Show 2 earlier versionsHide 2 earlier versions
  1. Primary completion date: Dec 31, 2022 to Sep 30, 2025
    • Study completion date: Dec 31, 2022 to Dec 31, 2025
    v3
  2. Primary and study completion dates: Dec 31, 2021 to Dec 31, 2022v2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Explore the associations of prenatal maternal anxiety to placental histologic findings, and the pro-inflammatory, anti-inflammatory, and immunoregulatory cells found in the placenta and determine the effect of maternal anxiety on the association between placental molecular changes on pregnancy and birth and infant outcomes.
Trial Details
NCT Number NCT04993742
Lead Sponsor Henry M. Jackson Foundation for the Advancement of Military Medicine
Collaborators: 59th Medical Wing, Brooke Army Medical Center, University of the Incarnate Word, Uniformed Services University of the Health Sciences
Conditions
(from sponsor)		 Placental Dysfunction, Prenatal Stress
Enrollment 150 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov