Clinical Trial

Left and Right Hemisphere Contributions to Speech Perception

Enrolling by Invitation
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Record status
This record was last updated June 15, 2025 (before its estimated December 31, 2025 completion). Its status may not reflect the trial's current state.
Summary
Left and right temporal brain areas are thought to contribute to speech perception, but the division of labor between left and right hemisphere regions is still unclear. Here we use transcranial magnetic stimulation (TMS) to stimulate left and right temporal foci and a vertex control site to temporarily disrupt activation at the stimulation site, using a "virtual lesion" approach to test the effect of stimulation site on a series of speech perception tasks. This portion of the project is basic research. However, since TMS is viewed as an intervention, studies involving TMS in this grant are considered clinical trials.
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2021-07-25; most recent amendment 2025-06-11.
Status change: Not Yet Recruiting → Enrolling by Invitation 2025-06-11
Trial Details
NCT Number NCT04989309
Lead Sponsor University of Connecticut
Collaborators: National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions Neural Bases of Speech Perception
Enrollment 26 participants
Start Date 2024-12-19
Primary Completion 2025-12-31 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-06-15