BRINK (BRain In Kidney Disease) Memory Study 2.0

In this study, the investigators will be looking at results of tests of memory and thinking and daily activities in a group of people without known chronic kidney disease (CKD) , and a group of CKD patients, and follow the participants for up to four more years, including after the participants start dialysis or receive a transplant. The investigators are doing this study to compare how often memory loss, confusion and difficulty with daily activities occur in those without and those with CKD. Additionally, the investigators are doing this study to identify risk factors for memory and thinking problems in CKD patients. The information received through the NDI will be utilized to help track our study population and help provide useful information regarding cause of death of those in our study.

NCT Number	NCT04975464
Lead Sponsor	Anne Murray Collaborators: National Institute on Aging (NIA), Minneapolis Veterans Affairs Medical Center, Mayo Clinic, HealthPartners Institute
Conditions	Chronic Kidney Diseases, Dementia, Dementia, Vascular, Stroke, Alzheimer Disease, Cognitive Decline, Cognitive Impairment, Cognitive Dysfunction +4 more
Enrollment	600 participants
Start Date	2011-11-15
Primary Completion	2026-05 (estimated)
Study Completion	2026-05 (estimated)
Updated on ClinicalTrials.gov	2025-11-04