Clinical Trial

Clarifying the Optimal Application of SLT Therapy Trial

Study acronym: COAST
Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye drop medications better than waiting for SLT to wear off before repeating it.
Protocol Amendment History 12 amendments
This ClinicalTrials.gov record has been amended 12 times since 2021-07-19; most recent amendment 2025-09-26.
Status change: Not Yet Recruiting → Recruiting 2022-07-12
Trial Details
NCT Number NCT04967989
Lead Sponsor University of Pittsburgh
Collaborators: National Eye Institute (NEI), West Virginia University
Conditions Glaucoma and Ocular Hypertension
Enrollment 790 participants
Start Date 2021-09-07
Primary Completion 2027-06-30 (estimated)
Study Completion 2027-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-14