Tooth Retention After Root Canal Treatment With Endomethasone N

The aim of root canal treatment, or endodontic treatment, is to treat pulpal or periapical diseases and thus transform a pathological tooth into a healthy, asymptomatic and functional entity on the dental arch. The diagnosis of pulp pathology is based on the symptomatology described by the patient, on data from the clinical examination and tests performed as well as the radiographic examinations. Different families of root canal sealers are used in endodontics: cements based on zinc oxide-eugenol (ZOE), resin-based materials, and calcium silicate-based cements. They provide a stable and hermetic sealing. The Septodont laboratory has developed and manufactured endomethasone N, a zinc oxide-eugenol root canal sealer. The aim of this retro-prospective PMCF study is to collect long term clinical and safety data on root canal obturation after treatment or retreatment by Endomethasone N.

NCT Number	NCT04945993
Lead Sponsor	Septodont
Conditions	Dental Root Canal Obturation
Enrollment	179 participants
Start Date	2021-07-02
Primary Completion	2026-10-21 (estimated)
Study Completion	2026-12-21 (estimated)
Updated on ClinicalTrials.gov	2026-05-06