Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial

Shoulder tendon tears are a common cause of shoulder pain and disability and after surgery the repaired tendon often does not heal. In this pilot study, men with low sex hormone levels will be randomly assigned to receive sex hormone therapy or placebo pills while healing from tendon repair surgery in their shoulder. Sex hormone therapy increases sex hormone levels, and the investigators will test whether these increased sex hormone levels show promise in improving tendon healing and patient shoulder function and pain.

NCT Number	NCT04944836
Lead Sponsor	University of Utah
Conditions	Rotator Cuff Tears
Enrollment	58 participants
Start Date	2023-03-09
Primary Completion	2028-07-01 (estimated)
Study Completion	2029-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-19