Clinical Trial

Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)

Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
This study will investigate if a medication (metformin) widely used in the treatment of diabetes could be re-purposed for the treatment of patients with a diagnosis of early stage ADPKD to slow the rate of kidney function decline, reducing morbidity and mortality and improving the quality of life for ADPKD patients.
Protocol Amendment History 15 amendments
This ClinicalTrials.gov record has been amended 15 times since 2021-06-16; most recent amendment 2026-03-26.
Status change: Not Yet Recruiting → Recruiting 2023-06-16
Trial Details
NCT Number NCT04939935
Lead Sponsor The University of Queensland
Conditions Autosomal Dominant Polycystic Kidney Disease
Enrollment 1,174 participants
Start Date 2022-11-29
Primary Completion 2030-12 (estimated)
Study Completion 2030-12 (estimated)
Updated on ClinicalTrials.gov 2026-03-31