Clinical Trial

Neoadjuvant Immunoradiotherapy in Head & Neck Cancer (NIRT 2-HNC)

Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The purpose of this study is to evaluate the efficacy of neoadjuvant immunoradiotherapy (NIRT) prior to surgery for the treatment of stage III and IVA HPV- HNSCC.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2021-06-16; most recent amendment 2026-04-07.
Status change: Recruiting → Active, Not Recruiting 2025-03-06
Status change: Not Yet Recruiting → Recruiting 2022-01-11
Trial Details
NCT Number NCT04938609
Lead Sponsor Providence Health & Services
Collaborators: Providence Cancer Center, Earle A. Chiles Research Institute
Conditions Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Enrollment 28 participants
Start Date 2022-01-11
Primary Completion 2027-01-11 (estimated)
Study Completion 2031-01-11 (estimated)
Updated on ClinicalTrials.gov 2026-04-09