Clinical Trial

Effect of Postoperative Prolonged Sedation With Dexmedetomidine After Successful Reperfusion With EVT on Long-term Prognosis in Patients With AIS (PPDET)

Recruiting Phase 4
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Summary
Dexmedetomidine can attenuate the activity of the sympathetic nervous system under stress response and improve ischemia-reperfusion injury. The investigators hypothesized that the prolonged sedation of dexmedetomidine after successful reperfusion of endovascular thrombectomy may improve the clinical outcome of acute ischemic stroke patients.
Protocol Amendment History 10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2021-06-03; most recent amendment 2023-12-19.
Trial Details
NCT Number NCT04916197
Lead Sponsor Beijing Chao Yang Hospital
Conditions Acute Ischemic Stroke
Enrollment 368 participants
Start Date 2024-03-01
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2023-12-20