Clinical Trial

ABLATE Versus PACE: PVI or AV Node Ablation and PM Implantation for Elderly Patients With Persistent AF

Active, Not Recruiting
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Record status
This record was last updated September 17, 2025 (before its estimated May 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
As patients age, symptom control and treatment of atrial fibrillation become equally difficult, often leading to increased hospitalization. ABLATE versus PACE is a prospective, randomized clinical trial comparing pacemaker implantation with AV node ablation with pulmonary vein isolation in terms of rehospitalization and quality of life in patients with persistent AF aged 75 years and older.
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2021-05-27; most recent amendment 2025-09-11.
Status change: Recruiting → Active, Not Recruiting 2025-09-11
Trial Details
NCT Number NCT04906668
Lead Sponsor St. Josefs-Hospital Wiesbaden GmbH
Collaborators: The German Heart Foundation
Conditions Atrial Fibrillation
Enrollment 196 participants
Start Date 2021-05-01
Primary Completion 2026-05-30 (estimated)
Study Completion 2027-04-30 (estimated)
Updated on ClinicalTrials.gov 2025-09-17