Clinical Trial

Mix and Match of the COVID-19 Vaccine for Safety and Immunogenicity

Study acronym: MOSAIC
Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The main goals of this study are to assess the immune response and safety of two different vaccines for first, second, third and fourth doses as well as for differing intervals between the first and second dose of two-dose vaccines.
Protocol Amendment History 10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2021-05-19; most recent amendment 2025-03-14.
Status change: Recruiting → Active, Not Recruiting 2023-03-17
Status change: Not Yet Recruiting → Recruiting 2021-06-07
Trial Details
NCT Number NCT04894435
Lead Sponsor Canadian Immunization Research Network
Collaborators: Canadian Center for Vaccinology, BC Children's Hospital Research Institute, Children's Hospital Research Institute of Manitoba, CHU de Quebec-Universite Laval, Ottawa Hospital Research Institute, Ontario Agency for Health Protection and Promotion, University of Toronto, Massachusetts General Hospital, Interior Health, McGill University Health Centre/Research Institute of the McGill University Health Centre
Conditions COVID-19
Enrollment 669 participants
Start Date 2021-05-20
Primary Completion 2024-11-15 (estimated)
Study Completion 2025-08-01 (estimated)
Updated on ClinicalTrials.gov 2025-03-18