Clinical Trial

Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy

Study acronym: CIPN
Active, Not Recruiting
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Summary
This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN). CIPN occurs when chemotherapy damages the nerves communicating between the brain, spinal cord, and the rest of the body. The usual approach for treating CIPN is treatment with drugs that help reduce symptoms of other types of neuropathy (for example, from diabetes). However, these drugs do not treat all symptoms of CIPN. Exercise may help to reduce CIPN symptoms.
Protocol Amendment History 16 amendments
This ClinicalTrials.gov record has been amended 16 times since 2021-05-11; most recent amendment 2026-04-22.
Status change: Completed → Active, Not Recruiting 2025-10-08
Status change: Recruiting → Completed 2025-08-28
Status change: Not Yet Recruiting → Recruiting 2022-01-31
Status change: Recruiting → Not Yet Recruiting 2021-12-07
Status change: Not Yet Recruiting → Recruiting 2021-09-20
Trial Details
NCT Number NCT04888988
Lead Sponsor University of Rochester NCORP Research Base
Collaborators: National Cancer Institute (NCI)
Conditions Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Enrollment 133 participants
Start Date 2022-02-25
Primary Completion 2025-10-20 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-04-24